新生兒在出生後首12個月，母體傳遞的免疫抗體逐步下降。活性HMP母乳益生菌及有機GOS益生元能有效刺激腸道生成SIgA活性免疫球蛋白1，形成人體黏膜免疫的關鍵因子，強化腸道屏障，抵禦外界不良因子/病原體，為寶寶早期免疫發育提供猶如母體般的保護。

Beams Of Light
Group 254

SIgA免疫球蛋白（Secretory Immunoglobulin A）是人體黏膜免疫系統中最重要一種抗體，主要存在於黏膜表面（例如腸道、呼吸道、口腔等）的分泌物，如唾液、眼淚、腸道及母乳等。它由腸道微生物群及其代謝物調節，對於維持免疫平衡同抵禦病原體時發揮關鍵作用4。

20250731_background_02

常見SIgA會從母乳中將有益微生物傳遞到嬰幼兒；而HMP+GOS擔任從腸道微生態中轉換過程帶來相同的效能6。

20250731_background_03
Group 202
Group 256
  1. Piloquet et al. Efficacy and safety of a symbiotic infant formula for the prevention of respiratory and gastrointestinal infections: A randomized controlled trial. The American Journal of Clinical Nutrition 119 (2024) 1259–1269
  2. Maldonado J et al. J Pediatr Gastroenterol Nutr 2012; 54(1): 55–61 ³ Gil-Campos M et al. Pharmacol Res 2012; 65(2): 231–238
  3. Secretory IgA: Linking microbes, maternal health, and infant health through human milk
  4. Mantis, N. J., Rol, N., & Corthésy, B. (2011). Secretory IgA’s complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunology, 4(6), 603–611. DOI: 10.1038/mi.2011.41
  5. Article’s discussion on SIgA and milk microbes (Section: Human milk SIgA and milk microbes).
  6. Olivares M and Lopez-Huertas E, 2018
  7. Maldonado et al. J Pediatr Gastroenterol Nutr 2012; 54: 55-61